A step along the way to the long-term goal of sequencing the euchromatic genomes of 50 independently sampled Drosophila melanogaster strains by high-density-oligonucleotide-microarray-based resequencing was to target a specific region. In this experiment 7 Mbp in each of 50 strains was targeted to validate and improve the platform, to establish a resequencing pipeline, and to develop the capacity and needed analytic tools for a population genetics project of this scale.
We are currently in the process of analyzing the data and preparing a manuscript
The sample of 50 D. melanogaster genomes sequenced consists of 40 highly inbred lines derived from a well studied North Carolina population and 10 lines from Malawi (chromosomes were genetically extracted into 27 stocks).
Target Regions
Resequencing Data Release 1.0